Depression, or major depressive disorder, is a mental health condition marked by an overwhelming feeling of sadness, isolation and despair that affects how a person thinks, feels and functions. While sadness, loneliness and grief are a normal part of the human experience, depression is a diagnosable health condition that has the potential to significantly interfere with a person’s daily life and even prompt thoughts of suicide. 

In 2020, an estimated 21 million adults in the United States, or 8.4% of all U.S. adults, had at least one major depressive episode, according to the National Institute of Mental Health (opens in new tab) (NIMH). Depression can affect people of all ages, races and socioeconomic classes and can strike at any time, with 18-25 year olds reporting the most instances of a major depressive episode (17%). 

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